ABOUT THE RESTORE TRIAL
The RESTORE trial is now fully enrolled and actively following subjects through the follow up period of the study. For more information, please visit the study site HERE.
ALVEOLAR RIDGE AUGMENTATION
Alveolar ridge augmentation is a surgical procedure used to preserve bone that has been lost due to tooth extraction, disease, or trauma, and is often critical to achieving sufficient bone volume for successful dental implant placement. Clinicians typically use materials (such as xenografts, allografts, or synthetics), which primarily rely on passive osteoconduction to support new bone growth. While widely adopted, these materials can be slow to incorporate and often leave significant residual graft material at the time of implant placement, increasing the risk of complications.
OSTEOADAPT™ DE AND AMP2™ TECHNOLOGY
Unlike traditional grafts, OsteoAdapt DE contains an osteoinductive component designed to actively promote and accelerate bone formation while minimizing residual material at the time of dental implant placement. The product utilizes AMP2™, Theradaptive’s proprietary, engineered variant of recombinant human bone morphogenetic protein-2 (BMP-2), enabling targeted stem cell recruitment and controlled bone regeneration. This approach is intended to reduce healing time, improve surgical outcomes, and offer a quicker path to implant readiness. The RESTORE trial will assess the safety and performance of OsteoAdapt DE in comparison to a standard xenograft bone graft.
