PRECLINICAL STUDIES

PRECLINICAL STUDIES
STUDY NAME
TRAUMA – LARGE ANIMAL LONG BONE REPAIR STUDY
Evaluation of AMP2 coated ReBOSSIS in the chronic caprine tibial defect mode
Sheep Illustration
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Study Objects
STUDY OBJECTIVE
1
Tibial Defect

Goat tibial defect showing controlled partial excision of cranial tibialis and gastrocnemius muscles and periosteal removal

2
ReBOSSIS + AMP2
Rebossis AMP2 Tibial Defect Rebossis AMP2
STUDY OUTCOMES
STRONG DOSE-DEPENDENT BONE FORMATION

FIGURE 1 Mean angular moment of inertia for bone density (density in Hounsfield Units plotted versus distance from the rod center) for each treatment group plotted with respect to radial anatomical orientation. The medium dose of AMP2 demonstrated equivalent efficacy to higher doses.

1
Bone Formation

COMPLETE REGENERATION WITH PRECISION

Complete Regeneration Precision Complete Regeneration
Bone 0
Bone 1
Bone 2
Bone 3
OUR NOVEL TECHNOLOGY

AMP2 has beaten the standard of care in evey preclinical study conducted to date. Our platform technology unleashes the regenerative potential of injured tissues.

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PARTNER WITH US

We are headquartered in Frederick, Maryland with other locations in Boston, Orlando, and Memphis.

We believe in the power of teams and have several partnerships that are advancing new therapies. If you are interested in exploring a partnership, contact us.