FOCUS AREAS

VASCULAR, SOFT TISSUE & ORTHOPEDIC REPAIR

Focus Areas
OUR NOVEL METHOD FOR TISSUE REPAIR
We are focusing on developing life-changing treatments for patients. By enhancing therapeutic performance using novel protein modifications, we are well equipped to deliver solutions for unmet needs and conquer current limitations in the field of regenerative medicine.
Current Limitations

THERE IS VIRTUALLY NO EFFECTIVE WAY TO DELIVER AND RETAIN POTENT BIOLOGICS AT IMPLANTATION SITES

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Devices do not retain therapeutic proteins at implant sites

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Systemic delivery of regenerative therapeutic proteins is not sufficiently targeted to be effective

Our Approach
SAFE AND PRECISE THERAPEUTICS DELIVERY

Devices are ill-suited to deliver biologics and biologics are ill-suited for targeted delivery. Our work bridges this divide. With our platform we can turn virtually any implant into a biologic delivery device – effectively a “biodevice”.

OUR REGENERATION PIPELINE
THERADAPTIVE PRODUCTS
Theradaptive Products Process Theradaptive Products Process 2
PARTNERED DEVELOPMENT
Partnered Development Process Partnered Development Process
Radiobutton Formal FDA Designation as a Class III Medical Device
CASE STUDIES
UNMET NEED
Spine
DISC DEGENERATION
900,000
SPINAL FUSIONS PER YEAR
LIMITATIONS

Bone Morphogenetic Protein 2 (BMP2) is a very potent protein that induces bone formation wherever it is placed. Despite the excellent spinal fusion rates promoted by this powerful molecule, adverse safety outcomes associated with BMP2 have limited its use.

OUR APPROACH
AMP2
AMP2
ADVANTAGE

We developed a proprietary variant called AMP2 (targetable BMP2) that binds devices extremely tightly. It allows for precise bone regeneration, greater efficacy, safety, and ease of use.

"BMP2 is a very powerful protein that drives bone formation in the body. Of course, it's a double-edged sword, because if you don't have a way to deliver it, you can have very negative side effects. With AMP2, bone will only form where the implant is. It's a beautiful way to control the delivery."
Luis Alvarez
Founder
LEARN ABOUT OUR GAME-CHANGING TECHNOLOGY
OUR PLATFORM